2024年
論文
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-
"Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity"
Mitsuhiro Machitani, Akira Nomura, Taro Yamashita, Mami Yasukawa, Saori Ueki, Ken-Ichi Fujita, Toshihide Ueno, Akio Yamashita, Yoshikazu Tanzawa, Masahiko Watanabe, Toshiyasu Taniguchi, Noriko Saitoh, Shuichi Kaneko, Yukinari Kato, Hiroyuki Mano, Kenkichi Masutomi
Nature Cell Biology 26, 6, 932-945 (2024).
2023年
論文
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"miR-125a-5p/miR-125b-5p contributes to pathological activation of angiotensin II-AT1R in mouse distal convoluted tubule cells by the suppression of Atrap"
Keigo Hirota, Akio Yamashita, Eriko Abe, Takahiro Yamaji, Kengo Azushima, Shohei Tanaka, Shinya Taguchi, Shunichiro Tsukamoto, Hiromichi Wakui, Kouichi Tamura
Journal of Biological Chemistry 299, 12, 105478 (2023).
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"Angiotensin II type 1 receptor-associated protein deletion combined with angiotensin II stimulation accelerates the development of diabetic kidney disease in mice on a C57BL/6 strain"
Shinya Taguchi, Kengo Azushima, Takahiro Yamaji, Toru Suzuki, Eriko Abe, Shohei Tanaka, Keigo Hirota, Shunichiro Tsukamoto, Ryutaro Morita, Ryu Kobayashi, Sho Kinguchi, Akio Yamashita, Hiromichi Wakui & Kouichi Tamura
Hypertension Research 47, 55–66 (2023).
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"Angiotensin II type 1 receptor-associated protein in immune cells: a possible key factor in the pathogenesis of visceral obesity"
Shunichiro Tsukamoto, Toru Suzuki, Hiromichi Wakui, Tatsuki Uehara, Juri Ichikawa, Hiroshi Okuda, Kotaro Haruhara, Kengo Azushima, Eriko Abe, Shohei Tanaka, Shinya Taguchi, Keigo Hirota, Sho Kinguchi, Akio Yamashita, Tomohiko Tamura, Kouichi Tamura
Metabolism 149, December, 155706 (2023).
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"Combination of sacubitril/valsartan and blockade of the PI3K pathway enhanced kidney protection in a mouse model of cardiorenal syndrome"
Shunichiro Tsukamoto, Hiromichi Wakui, Tatsuki Uehara, Yuka Shiba, Kengo Azushima, Eriko Abe, Shohei Tanaka, Shinya Taguchi, Keigo Hirota, Shingo Urate, Toru Suzuki, Takayuki Yamada, Sho Kinguchi, Akio Yamashita, Kouichi Tamura
European Heart Journal Open 3, 6, oead098 (2023).
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-
"An atlas of substrate specificities for the human serine/threonine kinome"
Jared L. Johnson, Tomer M. Yaron, Emily M. Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M. Cizin, Benjamin M. Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E. van Vlimmeren, Nicole Andrée-Busch, Norbert F. Käufer, Maxim V. Dorovkov, Alexey G. Ryazanov, Yuichiro Takagi, Edward R. Kastenhuber, Marcus D. Goncalves, Benjamin D. Hopkins, Olivier Elemento, Dylan J. Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D. Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V. Hornbeck, Benjamin E. Turk, Michael B. Yaffe & Lewis C. Cantley
Nature 613, 759–766 (2023).
2022年
論文
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"Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalization"
Eriko Abe, Akio Yamashita, Keigo Hirota, Takahiro Yamaji, Kengo Azushima, Shingo Urate, Toru Suzuki, Shohei Tanaka, Shinya Taguchi, Shunichiro Tsukamoto, Tatsuki Uehara, Hiromichi Wakui, Kouichi Tamura & Hidehisa Takahashi
Scientific Reports 12, 17376 (2022).
-
"Deficiency of the kidney tubular angiotensin II type1 receptor-associated protein ATRAP exacerbates streptozotocin-induced diabetic glomerular injury via reducing protective macrophage polarization"
Haruhara K, Suzuki T, Wakui H, Azushima K, Kurotaki D, Kawase W, Uneda K, Kobayashi R, Ohki K, Kinguchi S, Yamaji T, Kato I, Ohashi K, Yamashita A, Tamura T, Tsuboi N, Yokoo T, Tamura K.
Kidney International S0085-2538, 22, 00161-2 (2022).
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2021年
論文
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"Effects of tumor necrosis factor-α inhibition on kidney fibrosis and inflammation in a mouse model of aristolochic acid nephropathy"
Taguchi S, Azushima K, Yamaji T, Urate S, Suzuki T, Abe E, Tanaka S, Tsukamoto S, Kamimura D, Kinguchi S, Yamashita A, Wakui H, Tamura K.
Scientific Reports 11, 1, 23587 (2021).
-
-
"De novo ATP1A3 variants cause polymicrogyria"
Miyatake, Satoko; Kato, Mitsuhiro; Kumamoto, Takuma; Hirose, Tomonori; Koshimizu, Eriko; Matsui, Takaaki; Takeuchi, Hideyuki; Doi, Hiroshi; Hamada, Keisuke; Nakashima, Mitsuko;
Science Advances 7, 13, eabd2368 (2021).
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"Resistance to Tubulointerstitial Injury in a Mouse Remnant Kidney Model"
Tanaka, Shohei; Wakui, Hiromichi; Azushima, Kengo; Tsukamoto, Shunichiro; Yamaji, Takahiro; Urate, Shingo; Suzuki, Toru; Abe, Eriko; Taguchi, Shinya; Yamada, Takayuki;
(2021).
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2020年
論文
-
-
-
"The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation"
Shimada, Masaru; Yamashita, Akio; Saito, Manami; Ichino, Motohide; Kinjo, Takao; Mizuki, Nobuhisa; Klinman, Dennis M; Okuda, Kenji;
Scientific reports 10, 1, 1-14 (2020).
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"Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity"
Sasaki, Kazunori; Kojitani, Noriko; Hirose, Hiroko; Yoshihama, Yohei; Suzuki, Hidefumi; Shimada, Miho; Takayanagi, Ayumi; Yamashita, Akio; Nakaya, Masa-aki; Hirano, Hisashi;
Cell reports 31, 1, 107407 (2020).
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"Effects of Rikkunshito treatment on renal fibrosis/inflammation and body weight reduction in a unilateral ureteral obstruction model in mice"
Wakui, Hiromichi; Yamaji, Takahiro; Azushima, Kengo; Uneda, Kazushi; Haruhara, Kotaro; Nakamura, Akiko; Ohki, Kohji; Kinguchi, Sho; Kobayashi, Ryu; Urate, Shingo;
Scientific reports 10, 1, 1-11 (2020).
2019年
論文
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"Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line"
Yamaji, Takahiro; Yamashita, Akio; Wakui, Hiromichi; Azushima, Kengo; Uneda, Kazushi; Fujikawa, Yumiko; Haku, Sona; Kobayashi, Ryu; Ohki, Kohji; Haruhara, Kotaro;
Scientific reports 9, 1, 1-11 (2019).
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-
"Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension"
Kinguchi, Sho; Wakui, Hiromichi; Azushima, Kengo; Haruhara, Kotaro; Koguchi, Tomoyuki; Ohki, Kohji; Uneda, Kazushi; Matsuda, Miyuki; Haku, Sona; Yamaji, Takahiro;
Journal of the American Heart Association 8, 8, e012395 (2019).
-
"Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice"
Azushima, Kengo; Uneda, Kazushi; Wakui, Hiromichi; Ohki, Kohji; Haruhara, Kotaro; Kobayashi, Ryu; Haku, Sona; Kinguchi, Sho; Yamaji, Takahiro; Minegishi, Shintaro;
Scientific reports 9, 1, 1-10 (2019).
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"Functional Role of ATRAP, a Novel Receptor Binding Protein, in the Regulation of Renal Sodium Handling and Blood Pressure"
TAMURA, Kouichi; UNEDA, Kazushi; KOBAYASHI, Ryu; AZUSHIMA, Kengo; OHSAWA, Masato; MASUDA, Shin-ichiro; HAKU, Sona; OHKI, Kohji; HARUHARA, Kotaro; KINGUCHI, Sho;
Bulletin of the Society of Sea Water Science, Japan 73, 2, 54-58 (2019).
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"Translation-dependent unwinding of stem_loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs"
Mino, Takashi; Iwai, Noriki; Endo, Masayuki; Inoue, Kentaro; Akaki, Kotaro; Hia, Fabian; Uehata, Takuya; Emura, Tomoko; Hidaka, Kumi; Suzuki, Yutaka;
Nucleic acids research 47, 16, 8838-8859 (2019).
-
"A Receptor-Binding Molecule-Mediated Protective Tubular-Glomerular Interaction Against Diabetic Nephropathy by Promoting Tissue-Reparative Macrophage Polarization"
Haruhara, Kotaro; Wakui, Hiromichi; Azushima, Kengo; Kurotaki, Daisuke; Kawase, Wataru; Uneda, Kazushi; Kobayashi, Ryu; Ohki, Kohji; Kinguchi, Sho; Yamaji, Takahiro;
(2019).
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-
"N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation"
Yamasoba, Daichi; Sato, Kei; Ichinose, Takuya; Imamura, Tomoko; Koepke, Lennart; Joas, Simone; Reith, Elisabeth; Hotter, Dominik; Misawa, Naoko; Akaki, Kotaro;
Nature microbiology 4, 9, 1532-1544 (2019).
2018年
論文
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-
-
"Early enhanced leucine-rich α-2-glycoprotein-1 expression in glomerular endothelial cells of type 2 diabetic nephropathy model mice"
Wakui, Hiromichi; Azushima, Kengo; Haruhara, Kotaro; Kinguchi, Sho; Ohki, Kohji; Uneda, Kazushi; Kobayashi, Ryu; Matsuda, Miyuki; Yamaji, Takahiro; Yamada, Takayuki;
BioMed research international 2018 (2018).
-
"Angiotensin II type 1 receptor-associated protein inhibits angiotensin II-induced insulin resistance with suppression of oxidative stress in skeletal muscle tissue"
Ohki, Kohji; Wakui, Hiromichi; Kishio, Nozomu; Azushima, Kengo; Uneda, Kazushi; Haku, Sona; Kobayashi, Ryu; Haruhara, Kotaro; Kinguchi, Sho; Yamaji, Takahiro;
Scientific reports 8, 1, 1-12 (2018).
2017年
論文
-
"Adipocyte‐specific enhancement of angiotensin II type 1 receptor‐associated protein ameliorates diet‐induced visceral obesity and insulin resistance"
Azushima, Kengo; Ohki, Kohji; Wakui, Hiromichi; Uneda, Kazushi; Haku, Sona; Kobayashi, Ryu; Haruhara, Kotaro; Kinguchi, Sho; Matsuda, Miyuki; Maeda, Akinobu;
Journal of the American Heart Association 6, 3, e004488 (2017).
-
"An angiotensin II type 1 receptor binding molecule has a critical role in hypertension in a chronic kidney disease model"
Kobayashi, Ryu; Wakui, Hiromichi; Azushima, Kengo; Uneda, Kazushi; Haku, Sona; Ohki, Kohji; Haruhara, Kotaro; Kinguchi, Sho; Matsuda, Miyuki; Ohsawa, Masato;
Kidney international 91, 5, 1115-1125 (2017).
-
-
"Angiotensin II Type 1 receptor‐associated protein regulates kidney aging and lifespan independent of angiotensin"
Uneda, Kazushi; Wakui, Hiromichi; Maeda, Akinobu; Azushima, Kengo; Kobayashi, Ryu; Haku, Sona; Ohki, Kohji; Haruhara, Kotaro; Kinguchi, Sho; Matsuda, Miyuki;
Journal of the American Heart Association 6, 8, e006120 (2017).
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2016年
論文
-
"Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex"
Lopez-Perrote, Andres; Castano, Raquel; Melero, Roberto; Zamarro, Teresa; Kurosawa, Hitomi; Ohnishi, Tetsuo; Uchiyama, Akiko; Aoyagi, Kyoko; Buchwald, Gretel; Kataoka, Naoyuki;
Nucleic acids research 44, 4, 1909-1923 (2016).
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2015年
論文
-
-
"Renal Tubule Angiotensin II Type 1 Receptor_Associated Protein Promotes Natriuresis and Inhibits Salt‐Sensitive Blood Pressure Elevation"
Wakui, Hiromichi; Uneda, Kazushi; Tamura, Kouichi; Ohsawa, Masato; Azushima, Kengo; Kobayashi, Ryu; Ohki, Kohji; Dejima, Toru; Kanaoka, Tomohiko; Tsurumi‐Ikeya, Yuko;
Journal of the american heart association 4, 3, e001594 (2015).
-
"Mutations in the glutaminyl-tRNA synthetase gene cause early-onset epileptic encephalopathy"
Kodera, Hirofumi; Osaka, Hitoshi; Iai, Mizue; Aida, Noriko; Yamashita, Akio; Tsurusaki, Yoshinori; Nakashima, Mitsuko; Miyake, Noriko; Saitsu, Hirotomo; Matsumoto, Naomichi;
Journal of human genetics 60, 2, 97-101 (2015).
-
"Angiotensin II type 1 receptor binding molecule ATRAP as a possible modulator of renal sodium handling and blood pressure in pathophysiology"
Tamura, K; Wakui, H; Azushima, K; Uneda, K; Haku, S; Kobayashi, R; Ohki, K; Haruhara, K; Kinguchi, S; Matsuda, M;
Current medicinal chemistry 22, 28, 3210-3216 (2015).
2014年
論文
-
"aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface"
Satoh, Daisuke; Hirose, Tomonori; Harita, Yutaka; Daimon, Chikara; Harada, Tomonori; Kurihara, Hidetake; Yamashita, Akio; Ohno, Shigeo;
The Journal of Biochemistry 156, 2, 115-128 (2014).
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"A hemizygous GYG2 mutation and Leigh syndrome: a possible link?"
Imagawa, Eri; Osaka, Hitoshi; Yamashita, Akio; Shiina, Masaaki; Takahashi, Eihiko; Sugie, Hideo; Nakashima, Mitsuko; Tsurusaki, Yoshinori; Saitsu, Hirotomo; Ogata, Kazuhiro;
Human genetics 133, 2, 225-234 (2014).
-
"Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD"
Melero, Roberto; Uchiyama, Akiko; Casta_o, Raquel; Kataoka, Naoyuki; Kurosawa, Hitomi; Ohno, Shigeo; Yamashita, Akio; Llorca, Oscar;
Structure 22, 8, 1105-1119 (2014).
-
"Deletion of the angiotensin II type 1 receptor_associated protein enhances renal sodium reabsorption and exacerbates angiotensin II_mediated hypertension"
Ohsawa, Masato; Tamura, Kouichi; Wakui, Hiromichi; Maeda, Akinobu; Dejima, Toru; Kanaoka, Tomohiko; Azushima, Kengo; Uneda, Kazushi; Tsurumi-Ikeya, Yuko; Kobayashi, Ryu;
Kidney international 86, 3, 570-581 (2014).
-
"Effects of the angiotensin receptor blocker olmesartan on adipocyte hypertrophy and function in mice with metabolic disorders"
Maeda, Akinobu; Tamura, Kouichi; Wakui, Hiromichi; Ohsawa, Masato; Azushima, Kengo; Uneda, Kazushi; Kanaoka, Tomohiko; Kobayashi, Ryu; Ohki, Kohji; Matsuda, Miyuki;
BioMed research international 2014 (2014).
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2013年
論文
-
"Upstream stimulatory factors 1 and 2 mediate the transcription of angiotensin II binding and inhibitory protein"
Matsuda, Miyuki; Tamura, Kouichi; Wakui, Hiromichi; Maeda, Akinobu; Ohsawa, Masato; Kanaoka, Tomohiko; Azushima, Kengo; Uneda, Kazushi; Haku, Sona; Tsurumi-Ikeya, Yuko;
Journal of Biological Chemistry 288, 26, 19238-19249 (2013).
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"Angiotensin receptor_binding protein ATRAP/Agtrap inhibits metabolic dysfunction with visceral obesity"
Maeda, Akinobu; Tamura, Kouichi; Wakui, Hiromichi; Dejima, Toru; Ohsawa, Masato; Azushima, Kengo; Kanaoka, Tomohiko; Uneda, Kazushi; Matsuda, Miyuki; Yamashita, Akio;
Journal of the American Heart Association 2, 4, e000312 (2013).
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"The novel PAR-1-binding protein MTCL1 has crucial roles in organizing microtubules in polarizing epithelial cells"
Sato, Yoshinori; Akitsu, Masashi; Amano, Yoshiko; Yamashita, Kazunari; Ide, Mariko; Shimada, Kyoko; Yamashita, Akio; Hirano, Hisashi; Arakawa, Noriaki; Maki, Takahisa;
Journal of cell science 126, 20, 4671-4683 (2013).
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"Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity"
Azushima, Kengo; Tamura, Kouichi; Wakui, Hiromichi; Maeda, Akinobu; Ohsawa, Masato; Uneda, Kazushi; Kobayashi, Ryu; Kanaoka, Tomohiko; Dejima, Toru; Fujikawa, Tetsuya;
PLoS One 8, 10, e75560 (2013).
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-
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"The physiology and pathophysiology of a novel angiotensin receptor-binding protein ATRAP/Agtrap"
Tamura, Kouichi; Wakui, Hiromichi; Maeda, Akinobu; Dejima, Toru; Ohsawa, Masato; Azushima, Kengo; Kanaoka, Tomohiko; Haku, Sona; Uneda, Kazushi; Masuda, Shin-ichiro;
Current pharmaceutical design 19, 17, 3043-3048 (2013).
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"Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity"
Usuki, Fusako; Yamashita, Akio; Shiraishi, Tadafumi; Shiga, Atsushi; Onodera, Osamu; Higuchi, Itsuro; Ohno, Shigeo;
Proceedings of the National Academy of Sciences 110, 37, 15037-15042 (2013).
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"Activation of angiotensin II type 1 receptor-associated protein exerts an inhibitory effect on vascular hypertrophy and oxidative stress in angiotensin II-mediated hypertension"
Wakui, Hiromichi; Dejima, Toru; Tamura, Kouichi; Uneda, Kazushi; Azuma, Koichi; Maeda, Akinobu; Ohsawa, Masato; Kanaoka, Tomohiko; Azushima, Kengo; Kobayashi, Ryu;
Cardiovascular Research 100, 3, 511-519 (2013).
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"Enhanced angiotensin receptor-associated protein in renal tubule suppresses angiotensin-dependent hypertension"
Wakui, Hiromichi; Tamura, Kouichi; Masuda, Shin-ichiro; Tsurumi-Ikeya, Yuko; Fujita, Megumi; Maeda, Akinobu; Ohsawa, Masato; Azushima, Kengo; Uneda, Kazushi; Matsuda, Miyuki;
Hypertension 61, 6, 1203-1210 (2013).
2012年
論文
2011年
論文
-
"The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8"
Arias-Palomo, Ernesto; Yamashita, Akio; Fern_ndez, Israel S; N__ez-Ram_rez, Rafael; Bamba, Yumi; Izumi, Natsuko; Ohno, Shigeo; Llorca, Oscar;
Genes & development 25, 2, 153-164 (2011).
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-
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"Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex"
Fernandez, Israel S; Yamashita, Akio; Arias-Palomo, Ernesto; Bamba, Yumi; Bartolome, Ruben A; Canales, M Angeles; Teixid_, Joaqu_n; Ohno, Shigeo; Llorca, Oscar;
Nucleic acids research 39, 1, 347-358 (2011).
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"A novel role for hSMG-1 in stress granule formation"
Brown, James AL; Roberts, Tara L; Richards, Renee; Woods, Rick; Birrell, Geoff; Lim, Yi Chieh; Ohno, Shigeo; Yamashita, Akio; Abraham, Robert T; Gueven, Nuri;
Molecular and cellular biology 31, 22, 4417-4429 (2011).
-
"Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy"
Saitsu, Hirotomo; Osaka, Hitoshi; Sasaki, Masayuki; Takanashi, Jun-ichi; Hamada, Keisuke; Yamashita, Akio; Shibayama, Hidehiro; Shiina, Masaaki; Kondo, Yukiko; Nishiyama, Kiyomi;
The American Journal of Human Genetics 89, 5, 644-651 (2011).
2010年
論文
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"AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay"
Izumi, Natsuko; Yamashita, Akio; Iwamatsu, Akihiro; Kurata, Rie; Nakamura, Hiroki; Saari, Bonnie; Hirano, Hisashi; Anderson, Philip; Ohno, Shigeo;
Science signaling 3, 116, ra27-ra27 (2010).
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2009年
論文
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-
"SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay"
Yamashita, Akio; Izumi, Natsuko; Kashima, Isao; Ohnishi, Tetsuo; Saari, Bonnie; Katsuhata, Yukiko; Muramatsu, Reiko; Morita, Tomoko; Iwamatsu, Akihiro; Hachiya, Takahisa;
Genes & development 23, 9, 1091-1105 (2009).
2007年
論文
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"Human TOB, an antiproliferative transcription factor, is a poly (A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation"
Ezzeddine, Nader; Chang, Tsung-Cheng; Zhu, Wenmiao; Yamashita, Akio; Chen, Chyi-Ying A; Zhong, Zhenping; Yamashita, Yukiko; Zheng, Dinghai; Shyu, Ann-Bin;
Molecular and cellular biology 27, 22, 7791-7801 (2007).
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2006年
論文
-
"Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich disease fibroblasts"
Usuki, Fusako; Yamashita, Akio; Kashima, Isao; Higuchi, Itsuro; Osame, Mitsuhiro; Ohno, Shigeo;
Molecular Therapy 14, 3, 351-360 (2006).
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"Binding of a novel SMG-1_Upf1_eRF1_eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay"
Kashima, Isao; Yamashita, Akio; Izumi, Natsuko; Kataoka, Naoyuki; Morishita, Ryo; Hoshino, Shinichi; Ohno, Mutsuhito; Dreyfuss, Gideon; Ohno, Shigeo;
Genes & development 20, 3, 355-367 (2006).
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2005年
論文
2004年
論文
-
-
"UNR, a new partner of poly (A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant"
Chang, Tsung-Cheng; Yamashita, Akio; Chen, Chyi-Ying A; Yamashita, Yukiko; Zhu, Wenmiao; Durdan, Simon; Kahvejian, Avak; Sonenberg, Nahum; Shyu, Ann-Bin;
Genes & development 18, 16, 2010-2023 (2004).
2003年
論文
-
"Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7"
Ohnishi, Tetsuo; Yamashita, Akio; Kashima, Isao; Schell, Thomas; Anders, Kirk R; Grimson, Andrew; Hachiya, Takahisa; Hentze, Matthias W; Anderson, Philip; Ohno, Shigeo;
Molecular cell 12, 5, 1187-1200 (2003).
-
"Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor"
Baba, Masaya; Hirai, Syuiohi; Yamada-Okabe, Hisafumi; Hamada, Kenji; Tabuchi, Hisahiro; Kobayashi, Kazuki; Kondo, Keiichi; Yoshida, Minoru; Yamashita, Akio; Kishida, Takeshi;
Oncogene 22, 18, 2728-2738 (2003).
2002年
論文
2001年
論文
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"PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex"
Yamanaka, Tomoyuki; Horikoshi, Yosuke; Suzuki, Atsushi; Sugiyama, Yuki; Kitamura, Koichi; Maniwa, Rika; Nagai, Yoko; Yamashita, Akio; Hirose, Tomonori; Ishikawa, Hiroko;
Genes to Cells 6, 8, 721-731 (2001).
2000年
論文
-
"MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase"
Fukuyama, Keiko; Yoshida, Michihiko; Yamashita, Akio; Deyama, Tetsuya; Baba, Masaya; Suzuki, Atsushi; Mohri, Hiroshi; Ikezawa, Zenro; Nakajima, Hiroshi; Hirai, Syu-ichi;
Journal of Biological Chemistry 275, 28, 21247-21254 (2000).
1998年
論文
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"Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/mixed lineage kinase 2"
Hirai, Syu-ichi; Noda, Kumi; Moriguchi, Tetsuo; Nishida, Eisuke; Yamashita, Akio; Deyama, Tetsuya; Fukuyama, Keiko; Ohno, Shigeo;
Journal of Biological Chemistry 273, 13, 7406-7412 (1998).
1997年
論文
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"Involvement of protein kinase C in the activation of extracellular signal-regulated kinase 1/2 by UVC irradiation"
Zhuang, Shougang; Hirai, Syu-ichi; Mizuno, Keiko; Suzuki, Atsushi; Akimoto, Kazunori; Izumi, Yasushi; Yamashita, Akio; Ohno, Shigeo;
Biochemical and biophysical research communications 240, 2, 273-278 (1997).